Ryan and Jeff from Giant Bomb did a really good interview with Lead Writer Daniel Erickson on Everything from from queues, instancing to LS/DS permanence. Daniel is great at doing these interviews, as I personally would jump up and punch Jeff for constantly interrupting me.
Remember to listen to the part around 11:15 -12:15 as it is pretty much cut and paste what was happening on forums and websites as people were hearing about the game for the first time, and I still see people expressing concern that they’ll just be playing a single-player game presumably because “it’s Bioware.”””